PCF2024, Jealott's Hill
Introduction
The PhysChem Forum Committee are pleased to announce the next Physical Chemistry Symposium, PCF2024. This will be held at Syngenta, Jealott’s Hill International Research Centre, Bracknell, Berks, RG42 6EY, UK, on Monday 30th September and Tuesday 1st October 2024. The meeting title is "Closing the loop - measuring, modelling and predicting PhysChem properties". Registration will start earlier than usual, at 2pm on the Monday, with three talks starting at 3:30pm followed by gala dinner at 8pm. The Monday session will be held in the Hilton Doubletree St Annes Manor outside Wokingham, with the Tuesday meeting held at Syngenta Jealott's Hill (google map link). A bus will be available to take attendees from the hotel to the conference site on the Tuesday morning. A site map and site info leaflet can be found here.
Accomodation
The suggested hotel is the Hilton Doubletree St Annes Manor. You can book a discounted room via this link. The discount will also apply to the nights either side of the conference should attendees wish to arrive early or depart late. The final day for using the discount is Friday 16th August.
Registration
Registration for the meeting is now open - please complete this form.
Programme (provisional and subject to update)
Monday 30th September, Hilton Doubletree St Annes Manor
| Time | Session |
|---|---|
| Session 1 chair Nikita King, Syngenta | |
| 1400-1530 | Registration |
| 1530-1540 | Welcome and introduction to PCF2024 |
| 1540-1620 | New modalities - formulation challenges and opportunities for complex molecules (Johan Ulander, AstraZeneca Gothenburg) |
| 1620-1700 | Nonclassical zwitterions as a design principle to reduce lipophilicity without impacting permeability (Henrik Moebitz, Novaartis, Basel) |
| 1700-1730 | Tea break |
| 1730-1830 | Keynote - Changing face of drugs: implications for discovery, delivery and development (Marianne Ashford, AstraZeneca) |
| 1830-1930 | Social break |
| 1930-2200 | Symposium dinner |
Tuesday 1st October, Syngenta Jealott's Hill, Warfield, Bracknell, RG42 6EY, UK. Google map link here.
| Time | Session |
|---|---|
| Session 1 chair Toni Llinas, AstraZeneca | |
| 0830-0900 | Late registration and poster set-up |
| 0900-0910 | Syngenta site welcome |
| 0910-0950 | Agrochemical ADME and going digital (Jonathan Rains and Chris Baker, Syngenta, Jealott's Hill) |
| 0950-1030 | Developing amorphous solid dispersions with a MIDAS touch (Talbir Austin, SEDA, Cheadle) |
| 1030-1110 | Coffee break and poster viewing |
| Session 2 chair Stephane Rodde, Novartis | |
| 1110-1150 | Lipophilicity: a tale of three pHs (Ferdausi Mazumder, GlaxoSmithKline, Stevenage) |
| 1150-1210 | Flash poster presentations, 2 mins each |
| 1210-1340 | Lunch and poster viewing/Syngenta site tour (in parallel) |
| Session 3 chair Shenaz Bunally, GSK | |
| 1340-1420 | Targeted drug delivery to the lymphatic system (Pavel Gershkovich, School of Pharmacy, University of Nottingham) link to slides |
| 1420-1500 | Poster prize award followed by tea/coffee and poster viewing |
| Session 3 chair Jonathan Burley, School of Pharmacy, University of Nottingham | |
| 1500-1540 | Surrogation of biological properties by physico-chemical parameters (Marti Roses, University of Barcelona) |
| 1540-1620 | Development of solvation-based molecular descriptors for predicting physico-chemical properties and chromatographic retention times (David Palmer, University of Strathclyde) |
| 1620-1630 | Wrap-up and depart |
Posters
Posters are encouraged, please indicate if you are interested in bringing one when registering. Maximum dimensions A0, or 118 x 84 cm. Deadline for registering posters is Monday 16th September. Portrait is preferred but landscape can be accommodated.
Travel
The nearest airports to the Syngenta site are Heathrow (20 miles) and Gatwick (40 miles).
The nearest train stations are Bracknell (3 miles) and Maidenhead (6 miles). For the conference hotel, Bracknell train station is easiest. The X4 bus from Bracknell train station to Keephatch Gardens, then a short walk (ca. 5 minutes), will get you to the hotel. A conference bus will run from the hotel to the Syngenta site, departing at 7:30 am. For departure from the Syngenta site taxis can be booked and an announcement will be made at the conference.
If travelling by car please ensure you have registered your vehicle details via our registration form, and report to the security officer on duty at the entrance barrier.
The Jealott's Hill site
A map and info about the JH site is available on this link. For any special needs access or assistance please contact your host on the day, or the pcf organising team beforehand (via the registration e-mail).
Jealott’s Hill is a key site in Syngenta’s global Research and Development network and the company’s largest site for chemical and biological crop protection R&D, with over 1000 people and more than 45 nationalities represented. It is the largest commercial research facility in the UK dedicated to the introduction of new agricultural technologies for global use, supporting end to end scientific innovation from early discovery through to development and product support. Key activities at Jealott’s Hill include research into the discovery, design and characterisation of novel crop protection products along with the development of new formulation technologies and extensive human and environmental safety studies. The site also supports seeds research and has rapidly growing capabilities in digital and data science from R&D to the field. Jealott’s Hill contains a number of centres of scientific excellence, both chemical and biological, that support our worldwide R&D activities and is also a key hub for global R&D collaborations.
Supporters and sponsors
The PhysChem Forum is very grateful to our host Syngenta and our sponsors for helping us run PCF2024 as a free-to-attend event.
Syngenta At the Syngenta Group, our 60,000 people across more than 100 countries strive every day to transform agriculture through tailor-made solutions for the benefit of farmers, society and our planet – making us the world's most local agricultural technology and innovation partner. They are also very kindly hosting pcf2024!
Pion is a science-based company providing innovative technology, solutions, support and scientific expertise to the drug development industry. Pion empowers the pharmaceutical research community to use trusted data for the development of new and unique products that make a difference to people’s lives.
ACD/Labs ACD/Labs is a leading provider of scientific software, aiding decision-making and digital transformation in chemical and pharmaceutical R&D. Our science-centric solutions offer harmonized, AI-ready analytical, structural and molecular information, with FAIR-compliance. Our cloud-enabled technologies enable proliferation of chemically intelligent knowledge and workflow automation. For 30 years we have partnered with global organisations to enhance productivity and accelerate scientific innovation.
SEDA Pharmaceutical Development Services have a mission to maximise value through integrated Pharmaceutical Development and Clinical Pharmacology support. We enable rapid and efficient development of optimal medicinal products, from conventional to complex, through pragmatic and coherent scientific excellence.
We provide Clients with the experience and expertise found in the development functions of major pharmaceutical companies but with the speed and flexibility required by fast moving biotechs. We ensure that our systems, processes and project strategy have the agility to stay off the critical path. Enhancing the value proposition of our Clients is our contribution to bringing new, innovative therapies to patients rapidly and successfully.
The Solubility Company is a trusted preclinical CRO providing physicochemical measurement services based on the proprietary SPA method. The SPA platform technology enables rapid and accurate solubility screening from less than 100 µg of solid material and from anonymous samples! The technology is universal and works with all solvent types from aqueous media to organic solvents and formulation vehicles over a broad range of temperatures.
Our service laboratories are based in Helsinki, Finland and in Quakertown, Pennsylvania. The labs are operated by a highly skilled team with more than 50 years of experience in pharmaceutical research and development.
About the PhysChem Forum
We organise regular free-to-attend meetings with a focus on PhysChem in drug development. Our goal is to generate an environment for informed debate and discussion in a non-commercial setting with excellent networking opportunities. We are supported by many "BigPharma" and smaller pharmaceutical development companies through the input of the PhysChem organising committee. To join our exciting meetings please sign up to our e-mail list by dropping an e-mail to "info at physchem.org.uk"