PCF2023, Gothenburg


Photos from this conference are available at the bottom of this page. The poster prize winner was Saw Simeon from the Universoty of Uppsala.

The PhysChem forum PCF2023 is announced. The meeting, "Challenges and Future Directions of Preclinical Characterisation in ADMET and DMPK" will be hosted by AstraZeneca at the PGN Conference Center at their Gothenburg site in Sweden on 3rd and 4th October 2023. The meeting will start around 6pm on the 3rd and conclude around 5pm on the 4th. We are delighted to have a plenary lecture from Robert Young (Blue Burgundy, UK) on the theme of Natural Intelligence in Drug Discovery. The plenary lecture will be delivered in the evening of the 3rd October followed by the gala dinner at the Quality Hotel The Weaver. PhysChem Forum's meetings are free to attend and delegates are not charged for registration, however delegates will have to pay their own expenses including dinner at the plenary lecture (if they wish to attend), travel, and accommodation.


Delegates are responsible for arranging their own accommodation, the conference hotel is the Quality Hotel The Weaver. We have negotiated special rates which you can get using this booking code. Please note that after 4th September this discounted rate will no longer be valid. Pre-booked rooms will be released 3rd September.


Sweden has the Swedish Kronor as currency and Euros are in general not accepted, however payment by credit or debit card is accepted everywhere including for very small transactions. There is therefore no need to bring any local Swedish currency.

Travel to the symposium

Gothenburg has an international airport and a train station. The hotel can be reached from the airport by taxi or bus.

By bus: Busses (flygbussarna) run every 30 minutes from the airport to the City Centre. You can buy bus tickets in advance here and stopping at the Korsvägen (Svenska Mässan) stop, where tram 2 or 4 will take you to the hotel at Göteborgsvägen 91 (get out at the Krokslätts Fabriker tram stop). The hotel is a two minute walk from the tram stop. You can pay by credit card on the tram.

By taxi: You can pre-book your taxi from the airport to the hotel. Preferred transfer companies: VIP Taxi +46 (0)31 27 16 11, Taxi Göteborg +46 (0)31 650 000, Taxi Kurir +46 (0)31 27 27 27.

Tuesday 3rd October 2023

Keynote lecture followed by symposium dinner at the Quality Hotel The Weaver (Göteborgsvägen 91, 431 37 Mölndal). Google map link.

Wednesday 4th October 2023

At the AstraZeneca PGN Conference Center (Pepperedsleden 5, 431 50 Mölndal). A bus will take delegates from the hotel to the PGN Conference Center. Google map link and official site map.


Registration for the meeting is open via this link and you can also scan the QR code on the image above. Registration will (as ever) be free of charge, note however that there will be a charge for attending the conference dinner. Registration will close 15th September at the latest, and may close earlier if venue capacity becomes an issue. Register early to avoid disappointment!

Posters are encouraged, please indicate if you are interested in bringing one when registering. Maximum dimensions 180 x 88 cm.


The conference programme booklet can be downloaded from this link.

Tuesday 3rd October 2023 at the Quality Hotel The Weaver, Mölndal, Sweden.

Time Session
Chair Antonio Llinas (AstraZeneca, Sweden)
1730-1830 Drinks and registration
1830-1930 Natural Intelligence in Drug Discovery
Robert Young (Blue Burgundy, UK)
1930-2200 Symposium dinner

Wednesday 4th October 2023 at the AstraZeneca PGN Conference Center at Pepperedsleden 5, Gothenburg, Sweden. map

Time Session
Chair Antonio Llinas (AstraZeneca, Sweden)
0830-0900 Late registration and poster set-up
0900-0910 Welcome
Anders Holmén, VP Pharmaceutical Sciences, AstraZeneca
0910-0950 Design Principles for Balancing Lipophilicity and Permeability in beyond Rule of 5 Space
Henrik Moebitz (Novartis, Basel)
0950-1030 New method for absorption profiling of advanced drug discovery systems
Christel Bergström (Univ Uppsala)
1030-1100 Coffee break and poster viewing
Chair Shenaz Bunally (GSK)
1100-1140 Bio-mimetic HPLC based protein and phospholipid binding to predict in vivo distribution and toxicity of drug discovery compounds
Klara Valko (Bio-mimetic Chromatograpy Ltd, UK)
1140-1220 The influence of fluorination on lipophilicity
Bruno Linclau (Ghent University)
1220-1240 Flash poster session (authors introduce their posters, maximum 2 minutes each)
1240-1340 Lunch and poster viewing
Chair Stephane Rodde (Novartis)
1340-1420 Nanomedicine challenges and insights from in vitro LNP screening
Alan Sabirsh (AstraZeneca Gothenburg)
1420-1500 Physicochemical profiling for accelerating drug discovery: a high throughput approach for successful lead optimisation
Shenaz Bunally (GlaxoSmithKline)
1500-1530 Poster prize award, coffee, poster viewing
Chair Jonathan Burley (Univ Nottingham, UK)
1530-1610 Macrocycles in drug dicovery - what we know about property-based design
Jan Kihlberg (Univ Uppsala)
1610-1650 Biological-nanoparticles and cell-membrane interaction analysis using label-free surface-sensitive optical microscopy
Fredrik Höök (Chalmers Uni)
1650-1700 Wrap-up and depart

Supporters and sponsors

The PhysChem Forum is very grateful to our host AstraZeneca and our sponsors for helping us run PCF2023 as a free-to-attend event.

AstraZeneca is a global science-led patient-focused pharmaceutical company.They are dedicated to transforming the future of healthcare by unlocking the power of what science can do for people, society and the planet. They are also very kindly hosting pcf2023!

Fida Biosystems offer simple, accurate and fast detection and characterisation of proteins and nanoparticles under native conditions.

Pion is a science-based company providing innovative technology, solutions, support and scientific expertise to the drug development industry. Pion empowers the pharmaceutical research community to use trusted data for the development of new and unique products that make a difference to people’s lives.

Our Clients come to us when kinetic solubility data is not enough. The Solubility Company is a trusted preclinical CRO providing physicochemical measurement services based on the proprietary SPA method. The SPA technology enables rapid and accurate solubility screening from less than 100 µg of solid material from anonymous samples!

We offer a range of physicochemical measurement services based on the proprietary SPA method: thermodynamic/apparent/intrinsic/native solubility; dissolution rate; pKa; logP and logD; in buffer solutions, physiological solutions and organic solvents.

Our service laboratory is based in Helsinki, Finland and is operated by a highly skilled team with more than 50 years of experience in pharmaceutical development, high-tech R&D and management.

Selvita is a preclinical Contract Research Organisation providing multi-disciplinary support in resolving the unique challenges of research within the areas of drug discovery and drug development studies.

Selvita was established in 2007 and currently employs nearly 900 professionals, of which over 40 % hold a PhD degree. The company research sites are located in Krakow (HQ) and Poznan, Poland, as well as Zagreb, Croatia. Selvita's international offices are located in Cambridge, MA, and San Francisco Bay area in the U.S., as well as in Cambridge, UK.

ACD/Labs support drug discovery scientists using software developed by fellow scientists. They are specialists in informatics and a wide range of chemical disciplines, they have an international client base in the chemical, pharmaceutical, food and beverage, environment, agrochemical, flavour, fragrance, government and educational sectors.

Merck group provides infinite solutions to solve the toughest problems in life science in collaboration with the global scientific community. Our tools, services and digital platforms empower scientists and engineers at every stage, helping deliver breakthrough therapies more quickly. © Merck KGaA, Darmstadt, Germany.

SEDA Pharmaceutical Development Services have a mission to maximise value through integrated Pharmaceutical Development and Clinical Pharmacology support. We enable rapid and efficient development of optimal medicinal products, from conventional to complex, through pragmatic and coherent scientific excellence.

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Meeting report

A very successful and well attended meeting, thanks to all our sponsors and to our host.

About the PhysChem Forum

We organise regular free-to-attend meetings with a focus on PhysChem in drug development. Our goal is to generate an environment for informed debate and discussion in a non-commercial setting with excellent networking opportunities. We are supported by many "BigPharma" and smaller pharmaceutical development companies through the input of the PhysChem organising committee. To join our exciting meetings please sign up to our e-mail list by dropping an e-mail to "info at physchem.org.uk"