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PhysChem FORUM 8


The Physchem Forum Committee are pleased to announce our eighth Physical Chemistry Symposium to be held at Pfizer, Sandwich, UK on Wednesday 24th March 2010.


The programme will comprise a mixture of presentations and posters with ample opportunity dedicated to questions.


All posters are welcome but presentations are reserved for non-commercial work.

A prize (laptop computer), kindly sponsored by AATI, will be awarded to the best poster as decided by the committee.

Symposium Welcome Dinner

We shall be holding a 'Welcome Dinner', including a key-note presentation by Dr Dennis Smith (Pfizer) at the Abode Hotel, Canterbury, on the 23rd of March (the evening before the symposium).


There is no charge for this meeting. Attendance will only be allowed with prior registration.

Welcome Dinner, Tuesday 23rd March 2010

At the Abode Hotel, Canterbury, UK.

18.00 19.00

Pre-registration drinks

19.00 - 19.45

ADME and PhysChem: a mix like oil and water!
Dr Dennis Smith, Pfizer


Symposium Dinner

Symposium Programme, Wednesday 24th March 2010

At Pfizer, Sandwich, UK

Morning session - Chair: Nicola Colclough, AstraZeneca Alderley Park

9.00 9.20


9.20 10.00

Application of bio-mimetic HPLC for protein binding measurements in drug discovery
Dr Klara Valko (GSK)

10.00 10.40

An Improved High-Throughput Approach for the Determination of the Free Fraction of Drugs Strongly Bound to Plasma Proteins
Dr Joachim Schuhmacher (BayerScheringPharma)


11.00 11.40

The RED (Rapid Equilibrium Dialysis) 96-well plate for measurement of PPB (Plasma Protein Binding)
Dr Ruth Curran (Schering plough)

11.40 12.20

Permeability Measurements under Hydrodynamic Control
Prof Robert Dyrfe (University of Manchester)
12.20 - 14.00

Lunch & Poster session

Afternoon session - Chair: Kiyohiko Sugano, Pfizer, Sandwich

14.00 14.40

Biological membranes A hard act to follow
Dr Adrian Wright (Pfizer)

14.40 15.20

Ionization-Specific Prediction of Intestinal Permeability of Drugs
Dr Pranas Japertas (Pharma-algorithms)

15.20 16.00

Cell culture assays to predict oral drug absorption
Dr Sibylle Neuhoff (Simcyp)

16.00 - 16.05

Best poster award

Travel to the Symposium

Welcome Dinner, Tuesday 23rd March 2010

At the Abode Hotel, Canterbury.

Directions to the hotel can be found at their website

Main Symposium Wednesday 24th March 2010

At Pfizer, Ramsgate Road, Sandwich, Kent, CT13 9NJ, UK


  AATI who have kindly offered to provide a prize for the best poster (as judged by the committee).

Contact Information

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Last modified: 28 April 2008