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Physical Chemists by Physical Chemists
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Formulation Approaches for Poorly Soluble CompoundsDr Simon Pegg, Research Formulation Group, Pfizer Ltd, Sandwich, UK In my presentation I will cover identifying the causes of low exposure, what information is useful in formulation development, and then finally look at formulation options dependent on the compounds properties. This will include Self Emulsifying Drug Delivery systems (SEDDS) & Supersaturated SEDDS (s-SEDDS), Amorphous/Spray Dry Dispersions (SDDs), Nano Formulations and Particle Size Reduction. |
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