for Physical Chemists by Physical Chemists


Determination and Application of Aqueous Solubility in Pharmaceutical Discovery

Nicola Colclough, Associate Director Physical Chemistry, Astrazeneca

Solubility is a key parameter in pharmaceutical discovery facilitating the interpretation of biological data, aiding the interpretation of DMPK data and providing a risk assessment for candidate drugs entering development. This talk will give an overview of how solubility is determined in discovery at Astrazeneca and also provide some examples of how this data is being used to aid project progression.

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Last modified: 28 April 2008